TOTAL SYNTHESIS OF (+/-)-CITREOVIRAL, BASED ON A BIOGENETIC MODEL, AND FORMAL SYNTHESIS OF (+/-)-CITREOVIRIDIN

被引：12

作者：

BOWDEN, MC ^{[1
]}

PATEL, P ^{[1
]}

PATTENDEN, G ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 08期

关键词：

D O I：

10.1039/p19910001947

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of (+/-)-citreoviral, which co-occurs with citreoviridin, citreoviridinol, and citreodiol in Penicillium citreoviride, is described. The synthesis is based on a biogenetic model, and has as a key feature the elaboration of the dihydroxytetrahydrofuranyl ring portion 10 by an acid-catalysed cyclisation of the central epoxy alcohol intermediate 9 which is derived in ten steps from methyl tiglate.

引用

页码：1947 / 1950

页数：4

共 18 条

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[15] CHEMISTRY OF F1,F0-ATPASE INHIBITORS - STEREOSELECTIVE TOTAL SYNTHESES OF (+)-CITREOVIRAL AND (-)-CITREOVIRIDIN
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[16] ASYMMETRIC CIS - HYDROXYLATION VIA EPOXIDATION-CARBOXYLATION - A FORMAL SYNTHESIS OF (+)-CITREOVIRAL
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[17] TOTAL SYNTHESIS OF (+/-)-CITREOVIRIDIN
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[18] 1985, JUL OXF SYNTH M

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