PRENYLATED XANTHONES FROM GARCINIA-LIVINGSTONEI

被引:42
作者
SORDATDISERENS, I
ROGERS, C
SORDAT, B
HOSTETTMANN, K
机构
[1] SWISS INST EXPTL CANC RES, CH-1066 EPALINGES, SWITZERLAND
[2] UNIV DURBAN WESTVILLE, DEPT CHEM, DURBAN 4000, SOUTH AFRICA
关键词
GARCINIA-LIVINGSTONEI; GUTTIFERAE; ROOT BARK; PRENYLATED XANTHONES; 2D NMR; ANTIFUNGAL; CYTOINHIBITION;
D O I
10.1016/0031-9422(91)83061-O
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Five prenylated xanthones have been isolated from the root bark of Garcinia livingstonei of which four are novel natural products. The xanthone, 12b-hydroxy-des-D-garcigerrin A was previously isolated from G. gerrardii. Structure elucidation was achieved by a combination of one- and two-dimensional NMR spectroscopic techniques, mass spectroscopy and chemical methods. Two compounds are fungicidal against Cladosporium cucumerinum, a plant pathogenic fungus, whereas a third shows growth inhibitory activity against human colon carcinoma cell lines.
引用
收藏
页码:313 / 316
页数:4
相关论文
共 13 条