GRANULOCYTIC SARCOMA PRECEDING ACUTE-LEUKEMIA - REPORT OF 6 CASES

被引:0
作者
KRAUSE, JR
机构
[1] Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
关键词
D O I
10.1002/1097-0142(197909)44:3<1017::AID-CNCR2820440333>3.0.CO;2-I
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
An unusual case of granulocytic sarcoma presenting in a pericardial effusion following trauma and preceding acute myelogenous leukemia (AML) by 8 months is presented. Five additional cases of granulocytic sarcoma preceding leukemia collected by the author are also tabulated. Granulocytic sarcoma in a nonautopsy population of myelogenous leukemic patients was found to be 2.9%. When presenting in an extramedullary site, especially preceding peripheral blood and bone marrow manifestations of leukemia, a misdiagnosis of histiocytic lymphoma may result. In questionable cases, other techniques including the naphthol‐ASD‐chloroacetate stain, touch imprints, immunoperoxidase stain for lysozyme, and electron microscopy should be utilized. Although only a small series, the most recent cases have shown induction/remission and survival characteristics of AML patients without granulocytic sarcoma. Copyright © 1979 American Cancer Society
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页码:1017 / 1021
页数:5
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