FINE-NEEDLE ASPIRATION OF A SOLITARY PULMONARY NODULE FOLLOWING TREATMENT OF METASTATIC GIANT-CELL TUMOR OF BONE

被引：6

作者：

POWERS, CN

BULL, JM

RAVAL, P

SCHMIDT, WA

机构：

[1] Department of Pathology and Laboratory Medicine and, Medical School, University of Texas Health Science Center, the Department of Internal Medicine, Houston, Texas

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1991年 / 7卷 / 03期

关键词：

FINE-NEEDLE ASPIRATION; SOLITARY PULMONARY NODULE; GIANT-CELL TUMOR;

D O I：

10.1002/dc.2840070315

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Giant cell tumor (GCT) of bone is a local, variably aggressive neoplasm with high local recurrence and occassional pulmonary metastases. Radiographically guided fine-needle aspiration (FNA) plays a large role in establishing a tissue diagnosis of lung metastases prior to therapeutic intervention. We present a patient with histologically proven pulmonary metastases from a femoral grade II GCT. These lesions were obliterated with combination HT-CT (hyperthermia and chemotherapy). The patient subsequently developed another pulmonary nodule at a site previously occupied by a GCT metastatic deposit. Radiographically guided FNA revealed that this new lesion was an adenocarcinoma, apparently of pulmonary origin. We suggest that this second neoplasm arose within a scar that developed after HT-CT ablation of one of the metastases. Additional intriguing features of this case are the effective HT-CT therapy of GCT metastatic to lung and the extended temporal course (some 16 yr from initial diagnosis to death).

引用

页码：286 / 289

页数：4

共 17 条

[1]

Jaffee HL, Lichtenstein L, Portis RB, Giant cell tumor of bone, Arch Pathol, 30, pp. 993-1031, (1940)

[2]

Dahlin DC, Cupps RE, Johnson EW, Giant cell tumor: a study of 195 cases, Cancer, 25, pp. 1061-1070, (1970)

[3]

Sannerkin NG, Malignancy, aggressiveness, and recurrence in giant cell tumor of bone, Cancer, 46, pp. 1641-1649, (1980)

[4]

Mella O, Dahl O, Bang G, Engedal H, Gothlin J, Lunde OD, Chemotherapy of a malignant, metastasizing giant cell tumor of bone, Cancer, 50, pp. 207-211, (1982)

[5]

Rock MG, Pritchard DJ, Unni KK, Metastases from histologically benign giant‐cell tumor of bone, J Bone Joint Surg, 66, pp. 269-274, (1984)

[6]

Pan P, Mackinnon WB, “Benign” giant cell tumor of thoracic vertebra with pulmonary metastasis, Can Med Assoc J, 87, pp. 1026-1029, (1962)

[7]

Greeson AA, Dahlin DC, Peterson LFA, Payne WS, “Benign” giant cell tumor of bone metastasizing to lung, Ann Thoracic Surg, 16, pp. 531-535, (1973)

[8]

Mirra JM, Ulich T, Magidson J, Kaiser L, Eckardt J, Gold R, A case of probable benign pulmonary “metastases” or implants arising from a giant cell tumor of bone, Clin Orthop Rel Res, 162, pp. 245-254, (1982)

[9]

Present DA, Bertoni F, Springfield O, Braylan R, Enneking WF, Giant cell tumor of bone with pulmonary and lymph node metastases, Clin Orthop Rel Res, 209, pp. 286-291, (1986)

[10]

Sneige N, Ayala AG, Carrasco CH, Murray J, Raymond AK, Giant cell tumor of bone: a cytologic study of 24 cases, Diagn Cytopathol, 1, pp. 111-117, (1985)

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