ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ISATIN N-MANNICH BASES

被引：40

作者：

KUPINIC, M

MEDICSARIC, M

MOVRIN, M

MAYSINGER, D

机构：

[1] UNIV ZAGREB, FAC PHARM & BIOCHEM, YU-41001 Zagreb, YUGOSLAVIA

[2] INST CONTROL DRUGS, Zagreb, YUGOSLAVIA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1979年 / 68卷 / 04期

关键词：

Antifungal activity—series of isatin and 5‐nitroisatin N‐Mannich bases screened; Antimicrobial activity—series of isatin and 5‐nitroisatin N‐Mannich bases screened; Isatin N‐Mannich bases—screened for antimicrobial and antifungal activities; Nitroisatin N‐Mannich bases—screened for antimicrobial and antifungal activities;

D O I：

10.1002/jps.2600680417

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antimicrobial and antifungal activities of 29 congeneric isatin N‐Mannich bases were investigated by testing against standard test microorganisms and 21 pathogenic Gram‐negative microorganisms. Considerable growth inhibition of Gram‐negative bacteria and yeasts and slight inhibition of Gram‐positive bacteria resulted when they were treated with the various N‐Mannich bases of isatin and 5‐nitroisatin, respectively. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：459 / 462

页数：4

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