DESIGN OF 3-(4-CARBOXYBENZOYL)-2-QUINOLINECARBOXALDEHYDE AS A REAGENT FOR ULTRASENSITIVE DETERMINATION OF PRIMARY AMINES BY CAPILLARY ELECTROPHORESIS USING LASER FLUORESCENCE DETECTION

被引：198

作者：

LIU, JP ^{[1
]}

HSIEH, YZ ^{[1
]}

WIESLER, D ^{[1
]}

NOVOTNY, M ^{[1
]}

机构：

[1] INDIANA UNIV,DEPT CHEM,BLOOMINGTON,IN 47405

来源：

ANALYTICAL CHEMISTRY | 1991年 / 63卷 / 05期

关键词：

D O I：

10.1021/ac00005a004

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Amino acids and peptides, from both standard solutions and biological samples, were successfully reacted with 3-(4-carboxybenzoyl)-2-quinolinecarboxaldehyde, at low concentration, to form highly fluorescent isoindole derivatives. The formed mixtures are effectively separated by high-performance capillary electrophoresis and their constituents detected by their laser-induced fluorescence signals. The minimum detectable quantities in the low attomole (10(-18) mol) range are encountered.

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页码：408 / 412

页数：5

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