EXPRESSION OF THE TRUNCATED ESCHERICHIA-COLI O6-METHYLGUANINE METHYLTRANSFERASE GENE IN REPAIR-DEFICIENT HUMAN-CELLS AND RESTORATION OF CELLULAR-RESISTANCE TO ALKYLATING-AGENTS

被引：34
作者：
ISHIZAKI, K
TSUJIMURA, T
FUJIO, C
YANGPEI, Z
YAWATA, H
NAKABEPPU, Y
SEKIGUCHI, M
IKENAGA, M
机构：
[1] TOYO SODA MFG CO LTD,BIOTECHNOL RES LAB,KANAGAWA 252,JAPAN
[2] KYUSHU UNIV 60,FAC MED,DEPT BIOCHEM,FUKUOKA 812,JAPAN
来源：
MUTATION RESEARCH | 1987年 / 184卷 / 02期
关键词：
D O I：
10.1016/0167-8817(87)90068-X
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
引用
收藏
页码：121 / 128
页数：8
相关论文
共 25 条
[1]   EXPRESSION IN MAMMALIAN-CELLS OF A TRUNCATED ESCHERICHIA-COLI GENE CODING FOR O-6-ALKYLGUANINE ALKYLTRANSFERASE REDUCES THE TOXIC EFFECTS OF ALKYLATING-AGENTS [J].
BRENNAND, J ;
MARGISON, GP .
CARCINOGENESIS, 1986, 7 (12) :2081-2084
[2]   REDUCTION OF THE TOXICITY AND MUTAGENICITY OF ALKYLATING-AGENTS IN MAMMALIAN-CELLS HARBORING THE ESCHERICHIA-COLI ALKYLTRANSFERASE GENE [J].
BRENNAND, J ;
MARGISON, GP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (17) :6292-6296
[3]   EXPRESSION OF THE ESCHERICHIA-COLI O-6-METHYLGUANINE-METHYLPHOSPHOTRIESTER METHYLTRANSFERASE GENE IN MAMMALIAN-CELLS [J].
BRENNAND, J ;
MARGISON, GP .
CARCINOGENESIS, 1986, 7 (01) :185-188
[4]   DEFECTIVE REPAIR OF ALKYLATED DNA BY HUMAN-TUMOR AND SV40-TRANSFORMED HUMAN CELL STRAINS [J].
DAY, RS ;
ZIOLKOWSKI, CHJ ;
SCUDIERO, DA ;
MEYER, SA ;
LUBINIECKI, AS ;
GIRARDI, AJ ;
GALLOWAY, SM ;
BYNUM, GD .
NATURE, 1980, 288 (5792) :724-727
[5]   ACTIVE-SITE AND COMPLETE SEQUENCE OF THE SUICIDAL METHYLTRANSFERASE THAT COUNTERS ALKYLATION MUTAGENESIS [J].
DEMPLE, B ;
SEDGWICK, B ;
ROBINS, P ;
TOTTY, N ;
WATERFIELD, MD ;
LINDAHL, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (09) :2688-2692
[6]   DEPLETION OF O-6-METHYLGUANINE-DNA-METHYLTRANSFERASE IN HUMAN-FIBROBLASTS INCREASES THE MUTAGENIC RESPONSE TO N-METHYL-N'-NITRO-N-NITROSOGUANIDINE [J].
DOMORADZKI, J ;
PEGG, AE ;
DOLAN, ME ;
MAHER, VM ;
MCCORMICK, JJ .
CARCINOGENESIS, 1985, 6 (12) :1823-1826
[7]   TRANSFER OF THE ESCHERICHIA-COLI O-6-METHYLGUANINE METHYLTRANSFERASE GENE INTO REPAIR-DEFICIENT HUMAN-CELLS AND RESTORATION OF CELLULAR-RESISTANCE TO N-METHYL-N'-NITRO-N-NITROSOGUANIDINE [J].
ISHIZAKI, K ;
TSUJIMURA, T ;
YAWATA, H ;
FUJIO, C ;
NAKABEPPU, Y ;
SEKIGUCHI, M ;
IKENAGA, M .
MUTATION RESEARCH, 1986, 166 (02) :135-141
[8]   THE CYTO-TOXIC AND MUTAGENIC EFFECTS OF ALKYLATING-AGENTS ON HUMAN LYMPHOID-CELLS ARE CAUSED BY DIFFERENT DNA LESIONS [J].
KARRAN, P ;
WILLIAMS, SA .
CARCINOGENESIS, 1985, 6 (05) :789-792
[9]   COMPLEMENTATION OF SENSITIVITY TO ALKYLATING-AGENTS IN ESCHERICHIA-COLI AND CHINESE-HAMSTER OVARY CELLS BY EXPRESSION OF A CLONED BACTERIAL-DNA REPAIR GENE [J].
KATAOKA, H ;
HALL, J ;
KARRAN, P .
EMBO JOURNAL, 1986, 5 (12) :3195-3200
[10]   CLONING OF THE ESCHERICHIA-COLI O-6-METHYLGUANINE AND METHYLPHOSPHOTRIESTER METHYLTRANSFERASE GENE USING A FUNCTIONAL DNA-REPAIR ASSAY [J].
MARGISON, GP ;
COOPER, DP ;
BRENNAND, J .
NUCLEIC ACIDS RESEARCH, 1985, 13 (06) :1939-1952
123