NUCLEOTIDE-SEQUENCE OF THE 5'-FLANKING REGION OF THE RAT TYPE-II HEXOKINASE GENE

被引：13

作者：

ICHIHARA, J ^{[1
]}

SHINOHARA, Y ^{[1
]}

KOGURE, K ^{[1
]}

TERADA, H ^{[1
]}

机构：

[1] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1260卷 / 03期

关键词：

5'-FLANKING REGION; PUTATIVE TRANSCRIPTIONAL FACTOR BINDING SITE; TYPE II HEXOKINASE GENE; (RAT);

D O I：

10.1016/0167-4781(94)00226-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In a previous study, we found that the steady state transcript level of type II hexokinase was specifically and remarkably elevated in rat hepatoma AH130 cells. To determine the molecular mechanism of transcriptional control of the type II hexokinase gene, we examined the nucleotide sequence of its S-flanking region and analyzed putative transcription factor binding sites. We also examined the type II hexokinase promoter activity by the chloramphenicol acetyltransferase (CAT) assay.

引用

页码：365 / 368

页数：4

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