LACK OF GLUCAGON RESPONSE TO HYPOGLYCEMIA IN DIABETES - EVIDENCE FOR AN INTRINSIC PANCREATIC ALPHA CELL DEFECT

被引：629

作者：

GERICH, JE ^{[1
]}

LANGLOIS, M ^{[1
]}

NOACCO, C ^{[1
]}

KARAM, JH ^{[1
]}

FORSHAM, PH ^{[1
]}

机构：

[1] UNIV CALIF, MET RES UNIT, SAN FRANCISCO, CA 94143 USA

来源：

SCIENCE | 1973年 / 182卷 / 4108期

关键词：

D O I：

10.1126/science.182.4108.171

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：171 / 173

页数：3

共 17 条

[1]

BUCHANAN KD, 1972, LANCET, V1, P1394

[2] DECREASED SENSITIVITY OF PANCREATIC BETA CELLS TO GLUCOSE IN PREDIABETIC AND DIABETIC SUBJECTS - GLUCOSE DOSE-RESPONSE STUDY [J].

CERASI, E ;

EFENDIC, S ;

LUFT, R .

DIABETES, 1972, 21 (04) :224-&

[3]

CERASI E, 1970, Hormone and Metabolic Research, V2, P246

[4]

FORSHAM PH, 1970, DIABETES MELLITUS TH

[5]

GERICH J E, 1973, Clinical Research, V21, P201

[6] IN-VITRO INHIBITION OF PANCREATIC GLUCAGON SECRETION BY DIPHENYLHYDANTOIN [J].

GERICH, JE ;

LEVIN, SR ;

GRODSKY, GM ;

FOSHAM, PH ;

CHARLES, MA .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1972, 35 (06) :823-+

[7]

GERICH JE, 1971, ACTA ENDOCRINOL-COP, V67, P401

[8] DETERMINATION OF PANCREATIC AND GUT GLUCAGON-LIKE IMMUNOREACTIVITY (GLI) IN NORMAL AND DIABETIC SUBJECTS [J].

HEDING, LG ;

RASMUSSEN, SM .

DIABETOLOGIA, 1972, 8 (06) :408-411

[9]

LUYCKX AS, 1972, GLUCAGON MOLECULAR P

[10] STIMULUS-SECRETION COUPLING OF GLUCOSE-INDUCED INSULIN RELEASE .3. UPTAKE OF CA-45 BY ISOLATED ISLETS OF LANGERHANS [J].

MALAISSE.F ;

MALAISSE, WJ .

ENDOCRINOLOGY, 1971, 88 (01) :72-+

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