ENHANCED MUTAGENIC EFFECT OF A 60 HZ TIME-VARYING MAGNETIC-FIELD ON NUMBERS OF AZIDE-INDUCED TA100 REVERTANT COLONIES

Forty-eight hours exposure to a two Gauss (0.2 mT) rms 60 Hz time varying sinusoidal electromagnetic field increased the number of azide induced TA100 revertant colonies of Salmonella typhimurium 14% as compared with controls in the ambient <2 milli-Gauss 60 Hz field. In the absence of the electromagnetic field, the numbers of mutant colonies grown within and outside the non-energized coil were nearly identical. With out azide, the number of ''spontaneous'' mutant colonies forming in the experimental field was not statistically significant from numbers of colonies not exposed to field effects. Experimental temperature variation of 2 degrees C had little effect on colony formation, and the enhanced production of revertant colonies in the presence of the magnetic field was maintained during continued culture for 5 additional days. (C) 1993 Wiley-Liss, Inc.