CHRONIC BULLOUS DISEASE OF CHILDHOOD AND ULCERATIVE-COLITIS

被引：25
作者：
HANDLEY, J
SHIELDS, M
DODGE, J
WALSH, M
BINGHAM, A
机构：
[1] Departments of Dermatology, Royal Victoria Hospital, Royal Belfast Hospital for Sick Children, Belfast
[2] Departments of Pathology, Royal Victoria Hospital, Royal Belfast Hospital for Sick Children, Belfast
[3] Departments of Paediatrics, Royal Victoria Hospital, Royal Belfast Hospital for Sick Children, Belfast
来源：
PEDIATRIC DERMATOLOGY | 1993年 / 10卷 / 03期
关键词：
D O I：
10.1111/j.1525-1470.1993.tb00371.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
A 12-year-old girl with ulcerative colitis (UC) treated by colectomy with rectal stump preservation, salazopyrin, and systemic steroids developed persistent mouth ulcers, cutaneous targetlike lesions, papulopustules, and bullae. The clinical, histologic, and immunopathologic features were typical of chronic bullous disease of childhood (CBDC). Although resistant to combined immunosuppressive therapy with low-dose prednisolone, cyclosporin, and thalidomide, striking remission of the mucocutaneous symptoms resulted with surgical resection of the diseased rectal stump. An etiologic association between CBDC and UC is postulated.
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页码：256 / 258
页数：3
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