DOSAGE OF OKT3 INDEPENDENT OF BODY-WEIGHT - A MISTAKE

被引：0

作者：

BACHOFEN, M

GALLATI, H

PRACHT, I

BOCK, H

LANDMANN, J

THIEL, G

机构：

来源：

TRANSPLANT INTERNATIONAL | 1992年 / 5卷

关键词：

IMMUNOSUPPRESSION; MONOCLONAL ANTIBODIES; OKT3; ANTITHYMOCYTE GLOBULIN;

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Comparing OKT3 and antithymocyte globulin (ATG) in a prospective study, the dosage difference in regard to body weight (ATG: dependent on body weight/OKT3: independent) does not introduce any obvious source of mistake concerning clinical effectiveness or side effects. One explanation for the lack of influence of body weight may be the high effectiveness of 5 mg of OKT3, reaching a maximal effect even with lower plasma levels in heavier patients. We wonder, therefore, whether the OKT3 dosage could be lowered.

引用

页码：S473 / S475

页数：3