THEOPHYLLINE NEUROTOXICITY IS UNAFFECTED BY GLYCEROL-INDUCED RENAL-FAILURE

被引：3

作者：

RAMZAN, I

机构：

[1] Pharmacy Department, The University of Sydney, Sydney

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1990年 / 37卷 / 03期

关键词：

Glycerol renal failure; Seizures; Theophylline neurotoxicity;

D O I：

10.1016/0091-3057(90)90032-D

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Glycerol acute renal failure (ARF) was examined to see if it alters theophylline (Th) neurotoxicity in rats. Concentrations of Th in serum, cerebrospinal fluid and in brain at seizure onset were similar in control and ARF rats infused with Th. Thus, glycerol ARF fails to alter Th neurotoxicity, an effect similar to that noted previously with uranyl nitrate but not with ureter ligation. © 1990.

引用

页码：583 / 585

页数：3