DIRECT ROLE OF DOPAMINE IN THE RAT SUBTHALAMIC NUCLEUS AND AN ADJACENT INTRAPEDUNCULAR AREA

被引：74

作者：

BROWN, LL

MAKMAN, MH

WOLFSON, LI

DVORKIN, B

WARNER, C

KATZMAN, R

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT BIOCHEM,BRONX,NY 10461

[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MOLEC PHARMACOL,BRONX,NY 10461

来源：

SCIENCE | 1979年 / 206卷 / 4425期

关键词：

D O I：

10.1126/science.505015

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The subthalamic nucleus, a clinically important component of the extrapyramidal motor system, and a lateral area extending into the peduncle contain catecholamine terminals and dopamine receptors coupled to adenylate cyclose. In addition, dopamine agonists administered in vivo enhance glucose utilization in the region. Thus, neuronal function in this region is directly affected by dopamine and dopaminergic drugs.

引用

页码：1416 / 1418

页数：3

共 23 条

[1]

AHN HS, 1976, BRAIN RES, V116, P437, DOI 10.1016/0006-8993(76)90492-3

[2] APOMORPHINE INCREASES GLUCOSE-UTILIZATION IN SUBSTANTIA NIGRA, SUBTHALAMIC NUCLEUS AND CORPUS STRIATUM OF RAT [J].