CHIRAL PHOSPHINOARYLDIHYDROOXAZOLES AS LIGANDS IN ASYMMETRIC CATALYSIS - PD-CATALYZED ALLYLIC SUBSTITUTION

被引：673

作者：

VONMATT, P ^{[1
]}

PFALTZ, A ^{[1
]}

机构：

[1] UNIV BASEL,INST ORGAN CHEM,ST JOHANNS RING 19,CH-4056 BASEL,SWITZERLAND

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1993年 / 32卷 / 04期

关键词：

D O I：

10.1002/anie.199305661

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enantioselectivities up to 99% ee and excellent yields under mild reaction conditions could be realized in allylic alkylations [Eq. (a)] with palladium catalysts prepared with the chiral ligands 1. Enantiomerically pure phosphinoaryldihydrooxazoles (1) are readily accessible from commercially available chiral amino alcohols. HNu = H2C(COOMe)2, H2C(COMe)2, HC(NHAc)(COOEt)2. (Figure Presented.) Copyright © 1993 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：566 / 568

页数：3

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