THE ANTENNAPEDIA-TYPE HOMEOBOX GENES HAVE EVOLVED FROM 3 PRECURSORS SEPARATED EARLY IN METAZOAN EVOLUTION

被引：118
作者：
SCHUBERT, FR
NIESELTSTRUWE, K
GRUSS, P
机构：
[1] MAX PLANCK INST BIOPHYS CHEM,MOLEK ZELLBIOL ABT,W-3400 GOTTINGEN,GERMANY
[2] MAX PLANCK INST BIOPHYS CHEM,BIOCHEM KINET ABT,W-3400 GOTTINGEN,GERMANY
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1993年 / 90卷 / 01期
关键词：
D O I：
10.1073/pnas.90.1.143
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The developmental control genes containing an Antennapedia-type homeobox are clustered in insects and vertebrates. The evolution of these genes was studied by the construction of evolutionary trees and by statistical geometry in sequence space. The comparative analysis of the homeobox sequences reveals the subdivision of the Antennapedia-type homeobox genes into three classes early in metazoan evolution. This observation suggests an important function of these genes even in the most primitive metazoans. Subsequent duplication events generated a cluster of at least five homeobox genes in the last common ancestor of insects and vertebrates. These genes later independently gave rise to the 13 groups of paralogous genes in vertebrates and to the 11 Antennapedia-type genes in the Drosophila complexes.
引用
收藏
页码：143 / 147
页数：5
相关论文
共 42 条
[1]   THE HUMAN HOX GENE FAMILY [J].
ACAMPORA, D ;
DESPOSITO, M ;
FAIELLA, A ;
PANNESE, M ;
MIGLIACCIO, E ;
MORELLI, F ;
STORNAIUOLO, A ;
NIGRO, V ;
SIMEONE, A ;
BONCINELLI, E .
NUCLEIC ACIDS RESEARCH, 1989, 17 (24) :10385-10402
[2]   HOX AND HOM - HOMOLOGOUS GENE CLUSTERS IN INSECTS AND VERTEBRATES [J].
AKAM, M .
CELL, 1989, 57 (03) :347-349
[3]  
AKAM M, 1988, DEVELOPMENT, V104, P123
[4]   A NOVEL, TISSUE-SPECIFIC, DROSOPHILA HOMEOBOX GENE [J].
BARAD, M ;
JACK, T ;
CHADWICK, R ;
MCGINNIS, W .
EMBO JOURNAL, 1988, 7 (07) :2151-2161
[5]   A HOMEOTIC GENE-CLUSTER IN THE RED FLOUR BEETLE [J].
BEEMAN, RW .
NATURE, 1987, 327 (6119) :247-249
[6]   NEMATODE HOMEOBOX CLUSTER [J].
BURGLIN, TR ;
RUVKUN, G ;
COULSON, A ;
HAWKINS, NC ;
MCGHEE, JD ;
SCHALLER, D ;
WITTMANN, C ;
MULLER, F ;
WATERSTON, RH .
NATURE, 1991, 351 (6329) :703-703
[7]   AN ANALYSIS OF THE ORIGIN OF METAZOANS, USING COMPARISONS OF PARTIAL SEQUENCES OF THE 28S RNA, REVEALS AN EARLY EMERGENCE OF TRIPLOBLASTS [J].
CHRISTEN, R ;
RATTO, A ;
BAROIN, A ;
PERASSO, R ;
GRELL, KG ;
ADOUTTE, A .
EMBO JOURNAL, 1991, 10 (03) :499-503
[8]   POSTERIOR PATTERN-FORMATION IN C-ELEGANS INVOLVES POSITION-SPECIFIC EXPRESSION OF A GENE CONTAINING A HOMEOBOX [J].
COSTA, M ;
WEIR, M ;
COULSON, A ;
SULSTON, J ;
KENYON, C .
CELL, 1988, 55 (05) :747-756
[9]   STRUCTURAL COMPLEXITY AND EVOLUTIONARY CONSERVATION OF THE DROSOPHILA HOMEOTIC GENE PROBOSCIPEDIA [J].
CRIBBS, DL ;
PULTZ, MA ;
JOHNSON, D ;
MAZZULLA, M ;
KAUFMAN, TC .
EMBO JOURNAL, 1992, 11 (04) :1437-1449
[10]   EVX2, A HUMAN HOMEOBOX GENE HOMOLOGOUS TO THE EVEN-SKIPPED SEGMENTATION GENE, IS LOCALIZED AT THE 5' END OF HOX4 LOCUS ON CHROMOSOME-2 [J].
DESPOSITO, M ;
MORELLI, F ;
ACAMPORA, D ;
MIGLIACCIO, E ;
SIMEONE, A ;
BONCINELLI, E .
GENOMICS, 1991, 10 (01) :43-50
12345