TOTAL SYNTHESIS OF ISOROBUSTIN

被引：25

作者：

BARTON, DHR

DONNELLY, DMX

FINET, JP

GUIRY, PJ

机构：

[1] NATL UNIV IRELAND UNIV COLL DUBLIN,DEPT CHEM,DUBLIN 4,IRELAND

[2] TEXAS A&M UNIV SYST,DEPT CHEM,COLLEGE STN,TX 77843

[3] UNIV PROVENCE,SREP LAB,CNRS,URA 1412,F-13397 MARSEILLE 13,FRANCE

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)88512-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of isorobustin 1 in four steps from 5-methoxyresorcinol proceeds in an overall yield of 34%. The key step involves the arylation of a 4-hydroxy-2H-1-benzopyran-2-one 6 by 3,4-methylenedioxyphenyllead triacetate 9 in a chemoselective and regioselective manner.

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收藏

页码：7449 / 7452

页数：4

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