THE ROLE OF PENICILLIN AMIDASES IN NATURE AND IN INDUSTRY

被引：100
作者：
VALLE, F
BALBAS, P
MERINO, E
BOLIVAR, F
机构：
[1] Centro de Investigación sobre Ingeniería Genética y Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Mor. C.P. 62271
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 01期
关键词：
D O I：
10.1016/0968-0004(91)90014-M
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Penicillin amidase (PA) is the enzyme used commercially for the production of semisynthetic penicillins. During the past decade, a detailed picture of the structure and regulation of the gene encoding this enzyme has emerged, revealing a variety of interesting features that are unique among microorganisms. Clues to the biological role of this enzyme have been provided, as well as new strategies for the commercial production and utilization of PA.
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页码：36 / 40
页数：5
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