NEUROENDOCRINOLOGICAL APPROACH FOR EXAMINING THE MECHANISMS OF ACTION OF TOKI-SHAKUYAKU-SAN (TJ-23) ON THE ACTIVITY OF TYROSINE-HYDROXYLASE IN THE BRAIN

被引：3

作者：

TORIIZUKA, K

HAGINO, N

TERASAWA, K

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT CELLULAR & STRUCT BIOL,SAN ANTONIO,TX 78284

[2] TOYAMA MED & PHARMACEUT UNIV,DEPT JAPANESE ORIENTAL KAMPO MED,TOYAMA,TOYAMA 93001,JAPAN

来源：

PHYTOTHERAPY RESEARCH | 1993年 / 7卷

关键词：

KAMPO MEDICINES; BRAIN TYROSINE HYDROXYLASE; RATS;

D O I：

10.1002/ptr.2650070721

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Administration of the Kampo medicine, TJ-23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ-23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ-23 induced similar effects.

引用

页码：S70 / S72

页数：3

共 5 条

[1] HAGINO N, 1988, INT CONGR SER, V768, P433
[2] HAGINO N, 1988, RECENT ADV PHARM KAM, P144
[3] EFFECT OF TOKI-SHAKUYAKU-SAN ON OVULATION INDUCED BY HUMAN MENOPAUSAL GONADOTROPIN IN RATS
KOYAMA, T
HAGINO, N
COTHRON, AW
SAITO, M
[J]. AMERICAN JOURNAL OF CHINESE MEDICINE, 1988, 16 (3-4): : 169 - 172
[4] HIGHLY SENSITIVE ASSAY FOR TYROSINE-HYDROXYLASE ACTIVITY BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
NAGATSU, T
OKA, K
KATO, T
[J]. JOURNAL OF CHROMATOGRAPHY, 1979, 163 (03): : 247 - 252
[5] TORIIZUKA K, 1989, PHYSIOLOGIST, V32, P205

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