NEUROENDOCRINOLOGICAL APPROACH FOR EXAMINING THE MECHANISMS OF ACTION OF TOKI-SHAKUYAKU-SAN (TJ-23) ON THE ACTIVITY OF TYROSINE-HYDROXYLASE IN THE BRAIN

被引：3

作者：

TORIIZUKA, K

HAGINO, N

TERASAWA, K

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT CELLULAR & STRUCT BIOL,SAN ANTONIO,TX 78284

[2] TOYAMA MED & PHARMACEUT UNIV,DEPT JAPANESE ORIENTAL KAMPO MED,TOYAMA,TOYAMA 93001,JAPAN

来源：

PHYTOTHERAPY RESEARCH | 1993年 / 7卷

关键词：

KAMPO MEDICINES; BRAIN TYROSINE HYDROXYLASE; RATS;

D O I：

10.1002/ptr.2650070721

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Administration of the Kampo medicine, TJ-23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ-23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ-23 induced similar effects.

引用

页码：S70 / S72

页数：3

共 5 条

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[2]

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HAGINO, N ;

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SAITO, M .

AMERICAN JOURNAL OF CHINESE MEDICINE, 1988, 16 (3-4) :169-172

[4] HIGHLY SENSITIVE ASSAY FOR TYROSINE-HYDROXYLASE ACTIVITY BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

NAGATSU, T ;

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KATO, T .

JOURNAL OF CHROMATOGRAPHY, 1979, 163 (03) :247-252

[5]

TORIIZUKA K, 1989, PHYSIOLOGIST, V32, P205

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