Alien Limb Syndrome Responsive to Amantadine in a Patient with Corticobasal Syndrome

被引：2

作者：

Aquino Gondim, Francisco de Assis ^{[1
]}

Leonel Tavares Junior, Jose Wagner ^{[1
]}

Morais, Arlindo A. ^{[1
]}

Gondim Sales, Paulo Marcelo ^{[1
]}

Wagner, Horta Goes ^{[1
]}

机构：

[1] Univ Fed Ceara, Hosp Univ Walter Cantidio, Neurol Div, Fortaleza, Ceara, Brazil

来源：

TREMOR AND OTHER HYPERKINETIC MOVEMENTS | 2015年 / 5卷

关键词：

Alien hand syndrome; amantadine; corticobasal syndrome;

D O I：

10.7916/D83FaNQ7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Corticobasal syndrome (CBS) is a complex neurodegenerative disorder associated with parkinsonism and alien limb syndrome. Dressing and ideomotor apraxia were reportedly responsive to amantadine. Case Report: A 79-year-old female was referred for evaluation of right hemiparesis. Neurological examination showed dementia, normal ocular movements, mild facial hypomimia, and bradykinesia with right hemiparesis. Nine years later, she developed alien limb syndrome and was diagnosed with CBS. After failure to respond to several medications, alien limb syndrome markedly improved with amantadine. Discussion: To the best of our knowledge, this is the first report of a consistent response of severe, forced dystonic alien limb syndrome to amantadine in a patient with CBS.

引用

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