LEUKOCYTE ADHESION MOLECULES

被引：39
作者：
CHAPMAN, PT
HASKARD, DO
机构：
[1] Rheumatology Unit, Dept. Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London
来源：
BRITISH MEDICAL BULLETIN | 1995年 / 51卷 / 02期
关键词：
D O I：
10.1093/oxfordjournals.bmb.a072962
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The last few years have seen an enormous expansion of knowledge regarding the role of cell surface adhesion molecules in biological processes. This article discusses the contribution that adhesion molecules make to the traffic of leukocytes into and within synovium and to the capacity of leukocytes to perform their specialised functions. Because of their importance in cellular interactions, adhesion molecules represent a major potential target for anti-inflammatory therapy in rheumatoid and other inflammatory arthritides.
引用
收藏
页码：296 / 311
页数：16
相关论文
共 80 条
[1]   ISOLATION AND CULTURE OF SYNOVIAL MICROVASCULAR ENDOTHELIAL-CELLS - CHARACTERIZATION AND ASSESSMENT OF ADHESION MOLECULE EXPRESSION [J].
ABBOT, SE ;
KAUL, A ;
STEVENS, CR ;
BLAKE, DR .
ARTHRITIS AND RHEUMATISM, 1992, 35 (04) :401-406
[2]   THE MECHANISMS OF ACTION OF NONSTEROIDAL ANTIINFLAMMATORY DRUGS [J].
ABRAMSON, SB ;
WEISSMANN, G .
ARTHRITIS AND RHEUMATISM, 1989, 32 (01) :1-9
[3]   INCREASED EXPRESSION OF P150,95 AND CR3 LEUKOCYTE ADHESION MOLECULES BY MONONUCLEAR PHAGOCYTES IN RHEUMATOID SYNOVIAL MEMBRANES - COMPARISON WITH OSTEOARTHRITIC AND NORMAL SYNOVIAL MEMBRANES [J].
ALLEN, CA ;
HIGHTON, J ;
PALMER, DG .
ARTHRITIS AND RHEUMATISM, 1989, 32 (08) :947-954
[4]   LEUKOCYTE ADHESION MOLECULES DEFICIENCY - ITS STRUCTURAL BASIS, PATHOPHYSIOLOGY AND IMPLICATIONS FOR MODULATING THE INFLAMMATORY RESPONSE [J].
ARNAOUT, MA .
IMMUNOLOGICAL REVIEWS, 1990, 114 :145-180
[5]   CD44 IS THE PRINCIPAL CELL-SURFACE RECEPTOR FOR HYALURONATE [J].
ARUFFO, A ;
STAMENKOVIC, I ;
MELNICK, M ;
UNDERHILL, CB ;
SEED, B .
CELL, 1990, 61 (07) :1303-1313
[6]   COLCHICINE AND METHOTREXATE REDUCE LEUKOCYTE ADHERENCE AND EMIGRATION IN RAT MESENTERIC VENULES [J].
ASAKO, H ;
KUBES, P ;
BAETHGE, BA ;
WOLF, RE ;
GRANGER, DN .
INFLAMMATION, 1992, 16 (01) :45-56
[7]   ENDOTHELIAL-LEUKOCYTE ADHESION MOLECULES [J].
BEVILACQUA, MP .
ANNUAL REVIEW OF IMMUNOLOGY, 1993, 11 :767-804
[8]   SELECTINS [J].
BEVILACQUA, MP ;
NELSON, RM .
JOURNAL OF CLINICAL INVESTIGATION, 1993, 91 (02) :379-387
[9]  
BLUE ML, 1993, LYMPHOKINE CYTOK RES, V12, P213
[10]   MONOCLONAL-ANTIBODY TO MURINE PECAM-1 (CD31) BLOCKS ACUTE-INFLAMMATION IN-VIVO [J].
BOGEN, S ;
PAK, J ;
GARIFALLOU, M ;
DENG, XH ;
MULLER, WA .
JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (03) :1059-1064
12345678