THE EFFECTS OF SCLERODERMA SERA ON ENDOTHELIAL-CELL SURVIVAL INVITRO

被引：7

作者：

ETOH, T ^{[1
]}

IGARASHI, A ^{[1
]}

IOZUMI, K ^{[1
]}

ISHIBASHI, Y ^{[1
]}

TAKEHARA, K ^{[1
]}

机构：

[1] UNIV TOKYO,FAC MED,DEPT DERMATOL,7-3-1 HONGO,BUKYO KU,TOKYO 113,JAPAN

来源：

ARCHIVES OF DERMATOLOGICAL RESEARCH | 1990年 / 282卷 / 08期

关键词：

SCLERODERMA; PLATELETS; GROWTH FACTOR; ENDOTHELIAL CELL SURVIVAL; ANTINUCLEAR ANTIBODY;

D O I：

10.1007/BF00371946

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The effects of sera and of platelet-poor plasma from patients with scleroderma on endothelial cell survival in vitro were studied. The survival ratio of rat heart endothelial cells was studied both in 10% test serum and in 10% platelet-poor plasma. Sera from patients with scleroderma decreased the survival ratio significantly when compared with sera from normal controls. In contrast, there was no significant difference between platelet-poor plasma from patients with scleroderma and that from normal controls. Our data indicate that platelets in the patients with scleroderma may cause vascular damage by affecting endothelial cell survival.

引用

页码：516 / 519

页数：4

共 50 条

[31] Effects of Maternal Serum on Permeability of Glomerular Endothelial Cell Membrane [J].

Du, Hui ;

Liu, Haiyi ;

Zhao, Jun ;

Wu, Yuanyuan ;

Gong, Xun ;

Zhou, Qiong ;

Xu, Jingjing ;

Li, Yuqi ;

Shi, Xinwei ;

Qiao, Fuyuan .

JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES, 2011, 31 (01) :17-20

[32] Modulation of Endothelial Cell Survival by an Inhibitor of Angiogenesis Thrombospondin-1: a Dynamic Balance [J].

O.V. Volpert .

Cancer and Metastasis Reviews, 2000, 19 :87-92

[33] Modulation of endothelial cell survival by an inhibitor of angiogenesis thrombospondin-1: a dynamic balance [J].

Volpert, OV .

CANCER AND METASTASIS REVIEWS, 2000, 19 (1-2) :87-92

[34] Primary Monocytes Regulate Endothelial Cell Survival Through Secretion of Angiopoietin-1 and Activation of Endothelial Tie2 [J].

Schubert, Shai Y. ;

Benarroch, Alejandro ;

Monter-Solans, Juan ;

Edelman, Elazer R. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2011, 31 (04) :870-875

[35] Effects of endothelial cells on proliferation and survival of human mesenchymal stem cells and primary osteoblasts [J].

Steiner, Dominik ;

Lampert, Florian ;

Stark, G. Bjoern ;

Finkenzeller, Guenter .

JOURNAL OF ORTHOPAEDIC RESEARCH, 2012, 30 (10) :1682-1689

[36] MODULATION OF EXTRACELLULAR-MATRIX GENE-EXPRESSION BY HEPARIN AND ENDOTHELIAL-CELL GROWTH-FACTOR IN HUMAN SMOOTH-MUSCLE CELLS [J].

TAN, EML ;

DODGE, GR ;

SORGER, T ;

KOVALSZKY, I ;

UNGER, GA ;

YANG, LD ;

LEVINE, EM ;

IOZZO, RV .

LABORATORY INVESTIGATION, 1991, 64 (04) :474-482

[37] Effects of Tamoxifen Versus Raloxifene on Retinal Capillary Endothelial Cell Proliferation [J].

Grigsby, Jeffery G. ;

Parvathaneni, Kalpana ;

Almanza, Miguel A. ;

Botello, Angelica M. ;

Mondragon, Albert A. ;

Allen, Donald M. ;

Tsin, Andrew T. C. .

JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2011, 27 (03) :225-233

[38] Effects of LY294002 on the function of retinal endothelial cell in vitro [J].

Di, Yu ;

Chen, Xiao-Long .

INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 2018, 11 (09) :1447-1450

[39] In Vitro Endothelial Cell Proliferation Assay Reveals Distinct Levels of Proangiogenic Cytokines Characterizing Sera of Healthy Subjects and of Patients with Heart Failure [J].

Voltan, Rebecca ;

Zauli, Giorgio ;

Rizzo, Paola ;

Fucili, Alessandro ;

Pannella, Micaela ;

Marci, Roberto ;

Tisato, Veronica ;

Ferrari, Roberto ;

Secchiero, Paola .

MEDIATORS OF INFLAMMATION, 2014, 2014

[40] Visual Recovery and Endothelial Cell Survival After Descemet Stripping Automated Endothelial Keratoplasty for Failed Penetrating Keratoplasty Grafts-A Cohort Study [J].

Tarantino-Scherrer, Janine N. ;

Kaufmann, Claude ;

Bochmann, Frank ;

Bachmann, Lucas M. ;

Thiel, Michael A. .

CORNEA, 2015, 34 (09) :1024-1029

← 1 2 3 4 5 →