INVITRO EFFECTS OF MELANOCYTOLYTIC AGENTS AND OTHER COMPOUNDS UPON DOMINANT HUMAN MELANOMA TYROSINASE ACTIVITY

被引：4

作者：

CHEN, YM ^{[1
]}

CHAVIN, W ^{[1
]}

机构：

[1] WAYNE STATE UNIV, DEPT BIOL, DETROIT, MI 48202 USA

来源：

EXPERIENTIA | 1978年 / 34卷 / 01期

关键词：

D O I：

10.1007/BF01921877

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The activity of dominant human melanoma tyrosinase isozyme was greatly decreased by certain reducing agents. The number and geometry of phenolic groups as well as free-SH group appear important for enzymic inhibition. © 1978 Birkhäuser Verlag.

引用

页码：21 / 22

页数：2

共 12 条

[1]

CHEM YM, 1974, CANCER RES, V34, P3192

[2]

Chen Y. M., 1972, PIGMENTATION ITS GEN, P593

[3]

CHEN YM, 1974, P SOC EXP BIOL MED, V145, P695

[4]

CHEN YM, 1972, P AM ASSOC CANC RES, V13, P6

[5] RADIOMETRIC ASSAY OF TYROSINASE AND THEORETICAL CONSIDERATIONS OF MELANIN FORMATION [J].

CHEN, YM ;

CHAVIN, W .

ANALYTICAL BIOCHEMISTRY, 1965, 13 (02) :234-&

[6]

CHEN YM, 1974, P AM ASSOC CANC RES, V15, P3

[7]

CHEN YM, 1973, P AM ASSOC CANC RES, V14, P104

[8] INCORPORATION OF TYROSINE CARBOXYL GROUPS AND UTILIZATION OF D-TYROSINE IN MELANOGENESIS [J].

CHEN, YM ;

CHAVIN, W .

ANALYTICAL BIOCHEMISTRY, 1969, 27 (03) :463-&

[9]

CHEN YM, 1971, P AM ASSOC CANC RES, V12, P68

[10]

CHEN YM, 1975, CANCER RES, V35, P606

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