INHIBITION OF THE DEGRADATION OF RECEPTOR-BOUND HUMAN CHORIO-GONADOTROPIN BY LEUPEPTIN

被引：19

作者：

ASCOLI, M ^{[1
]}

机构：

[1] VANDERBILT UNIV, SCH MED, DEPT BIOCHEM, NASHVILLE, TN 37232 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 586卷 / 03期

基金：

美国国家卫生研究院;

关键词：

(Leydig cell); Choriogonadotropin; Hormone degradation; Leupeptin; Lysosome; Steroidogenesis;

D O I：

10.1016/0304-4165(79)90051-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability of leupeptin to block the degradation of receptor-bound human choriogonadotropin has been studied. It was found that this compound inhibited hormone degradation and intracellular cathepsin B activity in a parallel fashion, without affecting hormone-stimulated steroidogenesis. © 1979.

引用

页码：608 / 614

页数：7

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