Scientific Opinion on Emerging and Novel Brominated Flame Retardants (BFRs) in Food EFSA Panel on Contaminants in the Food Chain

被引：48

作者：

Benford, Diane ^{[1
]}

Ceccatelli, Sandra ^{[1
]}

Cottrill, Bruce ^{[1
]}

DiNovi, Michael ^{[1
]}

Dogliotti, Eugenia ^{[1
]}

Edler, Lutz ^{[1
]}

Farmer, Peter ^{[1
]}

Fuerst, Peter ^{[1
]}

Hoogenboom, Laurentius ^{[1
]}

Knutsen, Helle Katrine ^{[1
]}

Haldorsen, Anne-Katrine Lundebye ^{[1
]}

Metzler, Manfred ^{[1
]}

Nebbia, Carlo Stefano ^{[1
]}

O'Keeffe, Michael ^{[1
]}

Rietjens, Ivonne ^{[1
]}

Schrenk, Dieter ^{[1
]}

Silano, Vittorio ^{[1
]}

van Loveren, Hendrik ^{[1
]}

Vleminckx, Christiane ^{[1
]}

Wester, Pieter ^{[1
]}

机构：

[1] EFSA, Parma, Italy

来源：

EFSA JOURNAL | 2012年 / 10卷 / 10期

关键词：

Emerging brominated flame retardants; novel brominated flame retardants; BFRs; occurrence; food; toxicology; human exposure; risk assessment;

D O I：

10.2903/j.efsa.2012.2908

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

EFSA was asked to deliver a scientific opinion on brominated flame retardants (BFRs) other than PBDEs, PBBs, HBCDDs, TBBPA and brominated phenols and their derivatives. The BFRs that are the subject of the current opinion, were classified in groups termed, emerging. and, novel. BFRs. Information on 17 emerging and 10 novel BFRs was collected. The information varied widely for these BFRs. There is a lack of experimental data on physico-chemical characteristics, stability/reactivity and current use and production volume of all the emerging and novel BFRs. Due to the very limited information on occurrence, exposure and toxicity, the CONTAM Panel could not perform a risk characterisation for any of the BFRs considered. Instead, an attempt was made to identify those BFRs that could be a potential health concern and should be considered first for future investigations. For this purpose the Panel first evaluated the available experimental data on occurrence in food, behaviour in the environment and toxicity. Secondly, a modelling exercise was performed focussing on the potential of the emerging and novel BFRs for persistence in the environment and for their possible bioaccumulation potential. There is convincing evidence that tris(2,3-dibromopropyl) phosphate (TDBPP) and dibromoneopentyl glycol (DBNPG) are genotoxic and carcinogenic, warranting further surveillance of their occurrence in the environment and in food. Based on the limited experimental data on environmental behaviour, 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE) and hexabromobenzene (HBB) were identified as compounds that could raise a concern for bioaccumulation. For the modelling exercise, the CONTAM Panel selected two environmental characteristics, overall persistence and potential for bioaccumulation, as being most relevant to provide insight into the possibility that emerging or novel BFRs might accumulate in the food chain, and thus might appear in food intended for human consumption. The modelling exercise identified ten additional BFRs that should be subjected to further in-depth studies. (C) European Food Safety Authority, 2012

引用

页数：133

共 255 条

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