An isolate alpha-fetoprotein producing gastric cancer liver metastasis emerged in a patient previously affected by radiation induced liver disease

被引：0

作者：

Cardinale, Vincenzo ^{[1
]}

De Filippis, Gianmaria ^{[2
]}

Corsi, Alessandro ^{[3
]}

La Penna, Augusto ^{[4
]}

Rossi, Michele ^{[5
]}

Catalano, Carlo ^{[2
]}

Bianco, Paolo ^{[3
]}

De Santis, Adriano ^{[4
]}

Alvaro, Domenico ^{[1
]}

机构：

[1] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Viale Univ 37, I-00185 Rome, Italy

[2] Sapienza Univ Rome, Dept Radiol, I-00185 Rome, Italy

[3] Sapienza Univ Rome, Dept Mol Sci, I-00185 Rome, Italy

[4] Sapienza Univ Rome, Dept Clin Med, I-00185 Rome, Italy

[5] Sapienza Univ Rome, St Andrea Hosp, Dept Radiol, I-00185 Rome, Italy

来源：

WORLD JOURNAL OF HEPATOLOGY | 2013年 / 5卷 / 07期

关键词：

Alpha-fetoprotein producing gastric cancer; Hepatoid adenocarcinoma; Liver metastasization; Radiation induced liver disease;

D O I：

10.4254/wjh.v5.i7.398

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We report a case of an isolated hepatic neoplasia which originated in a site of the liver previously affected by radiation induced liver disease (RILD) in a patient resected for gastric cancer and referred to us for high serum alpha-fetoprotein (AFP) levels. This case challenged us in distiguishing, even histologically, between primary liver cancer and AFP producing gastric cancer metastasis. Only a panel of immunohis-tochemical markers allowed the definitive diagnosis of liver metastasis of endodermal stem cell-derived and AFP producing gastric cancer. We discuss the criteria for a differential diagnosis, as well as the possible link between RILD and emergence of liver neoplasia. (C) 2013 Baishideng. All rights reserved.

引用

页码：398 / 403

页数：6

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