MUCIN GENE-EXPRESSION IN THE HUMAN ENDOCERVIX

被引：77

作者：

AUDIE, JP

TETAERT, D

PIGNY, P

BUISINE, MP

JANIN, A

AUBERT, JP

PORCHET, N

BOERSMA, A

机构：

[1] INSERM,U377,F-59045 LILLE,FRANCE

[2] HOP A CALMETTE,ANAT CYTOL PATHOL LAB C,LILLE,FRANCE

[3] HOP C HURIEZ,BIOCHIM LAB,LILLE,FRANCE

来源：

HUMAN REPRODUCTION | 1995年 / 10卷 / 01期

关键词：

ENDOCERVIX; IN-SITU HYBRIDIZATION; MUCIN GENE;

D O I：

10.1093/humrep/10.1.98

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In the human uterine endocervix, five out of the six human mucin genes investigated (MUC 2, MUC 3, MUC 4, MUC 5AC, MUC 5B and MUC 6) are expressed, whereas in some other mucosae the hybridization pattern demonstrates the expression of only two or three of these genes, The most intense labelling by in-situ hybridization is obtained significantly with MUC 4, predominantly during the luteal phase, The expression of the MUC 4 gene appears to be influenced by the oestro-progesterone ratio, During the ovulatory cycle, there are only a few differences concerning the variations of expression of all other MUC genes.

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页码：98 / 102

页数：5

相关论文

共 26 条

[1] EVIDENCE FOR DIFFERENT HUMAN TRACHEOBRONCHIAL MUCIN PEPTIDES DEDUCED FROM NUCLEOTIDE CDNA SEQUENCES [J].

AUBERT, JP ;

PORCHET, N ;

CREPIN, M ;

DUTERQUECOQUILLAUD, M ;

VERGNES, G ;

MAZZUCA, M ;

DEBUIRE, B ;

PETITPREZ, D ;

DEGAND, P .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1991, 5 (02) :178-185

[2] EXPRESSION OF HUMAN MUCIN GENES IN RESPIRATORY, DIGESTIVE, AND REPRODUCTIVE TRACTS ASCERTAINED BY IN-SITU HYBRIDIZATION [J].

AUDIE, JP ;

JANIN, A ;

PORCHET, N ;

COPIN, MC ;

GOSSELIN, B ;

AUBERT, JP .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1993, 41 (10) :1479-1485

[3]

BOBEK LA, 1993, J BIOL CHEM, V268, P20563

[4]

BRAGA VMM, 1993, J CELL SCI, V105, P397

[5]

Carlstedt I, 1989, Symp Soc Exp Biol, V43, P289

[6] ESTROGEN REGULATION OF THE CENTRAL ENZYMES INVOLVED IN O-LINKED AND N-LINKED GLYCOPROTEIN ASSEMBLY IN THE DEVELOPING AND THE ADULT-RABBIT ENDOCERVIX [J].

CHILTON, BS ;

KAPLAN, HA ;

LENNARZ, WJ .

ENDOCRINOLOGY, 1988, 123 (03) :1237-1244

[7]

DCRUZ OJ, 1993, FERTIL STERIL, V60, P1011

[8] DEGENERATE 87-BASE-PAIR TANDEM REPEATS CREATE HYDROPHILIC HYDROPHOBIC ALTERNATING DOMAINS IN HUMAN MUCIN PEPTIDES MAPPED TO 11P15 [J].

DUFOSSE, J ;

PORCHET, N ;

AUDIE, JP ;

DUPERAT, VG ;

LAINE, A ;

VANSEUNINGEN, I ;

MARRAKCHI, S ;

DEGAND, P ;

AUBERT, JP .

BIOCHEMICAL JOURNAL, 1993, 293 :329-337

[9] REGULATION OF MUCIN GENE-EXPRESSION IN SECRETORY EPITHELIAL-CELLS [J].

GOLLUB, EG ;

GOSWAMI, S ;

KOUBA, D ;

MAROM, Z .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 197 (02) :667-673

[10] HISTOLOGICAL DETECTION OF MESSENGER-RNAS WITH BIOTINYLATED SYNTHETIC OLIGONUCLEOTIDE PROBES [J].

GUITTENY, AF ;

FOUQUE, B ;

MOUGIN, C ;

TEOULE, R ;

BLOCH, B .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1988, 36 (06) :563-571