SEQUENTIAL RESPIRATORY SYNCYTIAL VIRUS AND CYTOMEGALOVIRUS PNEUMONIA FOLLOWING BONE-MARROW TRANSPLANTATION

被引：5
作者：
KAPELUSHNIK, J [1 ]
ENGELHARD, D [1 ]
MEHTA, J [1 ]
OR, R [1 ]
BRANDSTETTER, Y [1 ]
PICARD, E [1 ]
CIVIDALLI, G [1 ]
NAGLER, A [1 ]
机构：
[1] HADASSAH UNIV HOSP,DEPT PEDIAT,IL-91120 JERUSALEM,ISRAEL
来源：
JOURNAL OF MEDICAL VIROLOGY | 1995年 / 46卷 / 02期
关键词：
BONE MARROW TRANSPLANTATION; CYTOMEGALOVIRUS; FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; INTERSTITIAL PNEUMONIA; RESPIRATORY SYNCYTIAL VIRUS;
D O I：
10.1002/jmv.1890460216
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A 6-month-old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV- and CMV-induced lung injury in these life-threatening infections. (C) 1995 Wiley-Liss, Inc.
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页码：169 / 171
页数：3
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