Menstrual disorders are a common problem during adolescence. These disorders may cause significant anxiety for patients and their families. Menorrhagia is frequent debilitating symptoms in gynecological practice resulting in need for repeated curettage and hysterectomy with its attendant morbidity and mortality the etiology of menorrhagia is very diverse, it may be due to systemic conditions like endocrine disorders (thyroid dysfunction), or local lesions of the genital tract (endometrial hyper plasia, pelvic inflammatory disease, endometriosis, benign and malignant tumors) thyroid dysfunction is one of the common cause of menstrual irregularities. There are various menstrual disorders occurring in women, which may be a result of a cause specific to anatomy or it may be due to clotting abnormalities or hormonal causes. There are established linkages between hypothyroidism and menstrual irregularities. The objective of the study was to determine the frequency & type of menstrual irregularities associated with hypothyroidism. Fifty patients were selected for the clinical study, complete history, physical examination and investigations of all patients has carried out. Of which thirty nine patients showed irregular menstrual cycles whereas 11 had regular menstrual cycles. Investigational test performed included Blood test such as (T3, T4, TSH & blood hormones profile), Ultrasound ( pelvis), Thyroid scans, endometrial biopsy, Pap smear, high vaginal swab and test for confirmation of ovulation were carried out at CENAR Hospital Quetta. The Examination and tests revealed that menorrhagia in (n=21) cases, oligomenorrhea in (n=19), metrorrhagia in (n=7), polymenorrhea in (n=2), Amenorrhea in (n=2), Early Menarche in (n= 6) and primary-infertility in (n= 3) patients. The common problem was observed in age group was 25-45 years. Menorrhagia and oligimenorrhea were most regular irregularities found in this study where frequent cause was Hashimoto's Thyroiditis. It is concluded that menstrual irregularities increase with severity of hypothyroidism
