XENOBIOTIC METABOLISM IN HUMANIZED YEAST - ENGINEERED YEAST-CELLS PRODUCING HUMAN NADPH-CYTOCHROME-P-450 REDUCTASE, CYTOCHROME B5, EPOXIDE HYDROLASE AND P-450S

被引：35
|
作者：
URBAN, P [1 ]
TRUAN, G [1 ]
GAUTIER, JC [1 ]
POMPON, D [1 ]
机构：
[1] CHU NECKER ENFANTS MALAD,INSERM,U75,F-75015 PARIS,FRANCE
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 1993年 / 21卷 / 04期
关键词：
D O I：
10.1042/bst0211028
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：1028 / 1034
页数：7
相关论文
共 50 条
  • [1] Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast
    Hayashi, K
    Sakaki, T
    Kominami, S
    Inouye, K
    Yabusaki, Y
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2000, 381 (01) : 164 - 170
  • [2] ENHANCED INVIVO MONOOXYGENASE ACTIVITIES OF MAMMALIAN P450S IN ENGINEERED YEAST-CELLS PRODUCING HIGH-LEVELS OF NADPH-P450 REDUCTASE AND HUMAN CYTOCHROME-B5
    TRUAN, G
    CULLIN, C
    REISDORF, P
    URBAN, P
    POMPON, D
    GENE, 1993, 125 (01) : 49 - 55
  • [3] PURIFICATION OF MICROSOMAL CYTOCHROME-P-450, NADPH-CYTOCHROME-P-450 REDUCTASE, AND EPOXIDE HYDRATASE FROM HUMAN LIVER
    WANG, P
    GUENGERICH, FP
    NEAL, RA
    FEDERATION PROCEEDINGS, 1979, 38 (03) : 320 - 320
  • [4] ROTATION AND INTERACTIONS OF GENETICALLY EXPRESSED CYTOCHROME-P-450IA1 AND NADPH-CYTOCHROME-P-450 REDUCTASE IN YEAST MICROSOMES
    IWASE, T
    SAKAKI, T
    YABUSAKI, Y
    OHKAWA, H
    OHTA, Y
    KAWATO, S
    BIOCHEMISTRY, 1991, 30 (34) : 8347 - 8351
  • [5] DISTRIBUTION OF CYTOCHROMES-P-450, CYTOCHROME-B5, AND NADPH-CYTOCHROME-P-450 REDUCTASE IN AN ENTIRE HUMAN LIVER
    WATKINS, PB
    MURRAY, SA
    THOMAS, PE
    WRIGHTON, SA
    BIOCHEMICAL PHARMACOLOGY, 1990, 39 (03) : 471 - 476
  • [6] Reduction of cytochrome b5 by NADPH-cytochrome P450 reductase
    Guengerich, FP
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2005, 440 (02) : 204 - 211
  • [7] Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5 enzymes
    Shimada, T
    Mernaugh, RL
    Guengerich, FP
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2005, 435 (01) : 207 - 216
  • [8] Cytochrome P450 3A, NADPH cytochrome P450 reductase and cytochrome b5 in the upper airways in horse
    Tyden, E.
    Olsen, L.
    Tallkvist, J.
    Tjalve, H.
    Larsson, P.
    RESEARCH IN VETERINARY SCIENCE, 2008, 85 (01) : 80 - 85
  • [9] PURIFICATION AND PROPERTIES OF HUMAN PLACENTAL NADPH-CYTOCHROME-P-450 REDUCTASE
    MUTO, N
    TAN, L
    BIOCHEMISTRY AND CELL BIOLOGY, 1986, 64 (03) : 184 - 193
  • [10] NADPH-CYTOCHROME P-450 REDUCTASE OF YEAST MICROSOMES
    AOYAMA, Y
    YOSHIDA, Y
    KUBOTA, S
    KUMAOKA, H
    FURUMICHI, A
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 185 (02) : 362 - 369
12345