RECOMBINANT INTERFERON GAMMA AUGMENTS PHAGOCYTE SUPEROXIDE PRODUCTION AND X-CHRONIC GRANULOMATOUS-DISEASE GENE-EXPRESSION IN X-LINKED VARIANT CHRONIC GRANULOMATOUS-DISEASE

被引：141
作者：
EZEKOWITZ, RAB
ORKIN, SH
NEWBURGER, PE
机构：
[1] UNIV MASSACHUSETTS,SCH MED,DEPT PEDIAT,55 LAKE AVE N,WORCESTER,MA 01605
[2] CHILDRENS HOSP MED CTR,DIV HEMATOL ONCOL,BOSTON,MA 02115
[3] CHILDRENS HOSP MED CTR,HOWARD HUGHES MED INST,BOSTON,MA 02115
[4] HARVARD UNIV,SCH MED,DEPT PEDIAT,BOSTON,MA 02115
来源：
JOURNAL OF CLINICAL INVESTIGATION | 1987年 / 80卷 / 04期
关键词：
D O I：
10.1172/JCI113153
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：1009 / 1016
页数：8
相关论文
共 49 条
[1]  
BABIOR BM, 1984, BLOOD, V64, P959
[2]  
BABIOR BM, 1981, LEUKOCYTE FUNCTION, P1
[3]   LEUKOCYTE OXIDASE - DEFECTIVE ACTIVITY IN CHRONIC GRANULOMATOUS DISEASE [J].
BAEHNER, RL ;
NATHAN, DG .
SCIENCE, 1967, 155 (3764) :835-&
[4]   GAMMA-INTERFERON IS ABLE TO ENHANCE THE OXIDATIVE-METABOLISM OF HUMAN-NEUTROPHILS [J].
BERTON, G ;
ZENI, L ;
CASSATELLA, MA ;
ROSSI, F .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 138 (03) :1276-1282
[5]   A VARIANT FORM OF X-LINKED CHRONIC GRANULOMATOUS-DISEASE WITH NORMAL NITROBLUE TETRAZOLIUM SLIDE TEST AND CYTOCHROME-B [J].
BORREGAARD, N ;
CROSS, AR ;
HERLIN, T ;
JONES, OTG ;
SEGAL, AW ;
VALERIUS, NH .
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1983, 13 (03) :243-248
[6]   ACTIVATION BY GAMMA-INTERFERON OF HUMAN MACROPHAGE CAPABILITY TO PRODUCE TOXIC OXYGEN MOLECULES IS ACCOMPANIED BY DECREASED KM OF THE SUPEROXIDE-GENERATING NADPH OXIDASE [J].
CASSATELLA, MA ;
DELLABIANCA, V ;
BERTON, G ;
ROSSI, F .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 132 (03) :908-914
[7]   SUPEROXIDE GENERATION BY DIGITONIN-STIMULATED GUINEA-PIG GRANULOCYTES - BASIS FOR A CONTINUOUS ASSAY FOR MONITORING SUPEROXIDE PRODUCTION AND FOR STUDY OF ACTIVATION OF GENERATING SYSTEM [J].
COHEN, HJ ;
CHOVANIEC, ME .
JOURNAL OF CLINICAL INVESTIGATION, 1978, 61 (04) :1081-1087
[8]   DEFECTIVE SUPEROXIDE PRODUCTION BY GRANULOCYTES FROM PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE [J].
CURNUTTE, JT ;
WHITTEN, DM ;
BABIOR, BM .
NEW ENGLAND JOURNAL OF MEDICINE, 1974, 290 (11) :593-597
[9]  
CURNUTTE JT, 1986, CLIN RES, V34, P455
[10]  
DINAUER M, 1987, CLIN RES, V35, P598
12345