IMAGING OF BIOMOLECULES WITH THE SCANNING TUNNELING MICROSCOPE - PROBLEMS AND PROSPECTS

被引：109

作者：

SALMERON, M ^{[1
]}

BEEBE, T ^{[1
]}

ODRIOZOLA, J ^{[1
]}

WILSON, T ^{[1
]}

OGLETREE, DF ^{[1
]}

SIEKHAUS, W ^{[1
]}

机构：

[1] UNIV CALIF LAWRENCE LIVERMORE NATL LAB,LIVERMORE,CA 94550

来源：

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A-VACUUM SURFACES AND FILMS | 1990年 / 8卷 / 01期

关键词：

D O I：

10.1116/1.576361

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The capabilities of the scanning tunneling microscope as a tool to study the morphology and structure of adsorbed biomolecules are reviewed in view of recent experimental results. Problems such as electrical conductivity of the biomolecules, fixation to the substrate and identification are analyzed in detail. In particular, the role of tip-surface interaction giving rise to repulsive forces is illustrated. It is concluded that fixation rather than conductivity is the major obstacle to the use of the STM for biological imaging. © 1990, American Vacuum Society. All rights reserved.

引用

页码：635 / 641

页数：7

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