ON ENANTIOSELECTIVE DEPROTONATION - SYNTHESIS AND CRYSTAL-STRUCTURE OF A CHIRAL AMIDOLITHIUM TETRAHYDROFURAN COMPLEX

被引：27

作者：

EDWARDS, AJ

HOCKEY, S

MAIR, FS

RAITHBY, PR

SNAITH, R

SIMPKINS, NS

机构：

[1] UNIV CAMBRIDGE, CHEM LAB, LENSFIELD RD, CAMBRIDGE CB2 1EW, ENGLAND

[2] UNIV NOTTINGHAM, DEPT CHEM, NOTTINGHAM NG7 2RD, ENGLAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 25期

关键词：

D O I：

10.1021/jo00077a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantioselective base (RR')-bis(1-phenylethyl)amidolithium (1) was crystallized from THF/hexane and characterized by X-ray crystallography as a bis-THF-solvated cyclic dimer which adopts a conformation that maximizes methyllithium contacts, inconsistent with previous rationalizations of its enantioselectivity in enolizations of cyclic ketones.

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页码：6942 / 6943

页数：2

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