RECENT PROGRESS IN THE SYNTHESIS OF BUTENOLIDE CAROTENOIDS AND RETINOIDS

被引：40

作者：

ITO, M

机构：

[1] Kobe Women's College of Pharmacy, Motoyamakita-machi, Kobe, 658, Higashinada-ku

来源：

PURE AND APPLIED CHEMISTRY | 1991年 / 63卷 / 01期

关键词：

D O I：

10.1351/pac199163010013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two kinds of method (the Witting and sulphone methods) to prepare 4-alkylidenebutenolides are described. An empirical rule regarding the NMR chemical shifts of H-3 in 4-alkylidenebutenolides displaying an extended conjugaed system at the C-2 position is shown. Total synthesis of racemic peridinin and pyrrhoxanthin has been accomplished by means of the sulphone method and optically active peridinin has been synthesised. Recent work on the synthesis of butenolide retinoids is also described.

引用

页码：13 / 22

页数：10

共 26 条

[1] CAROTENOIDS AND RELATED-COMPOUNDS .38. SYNTHESIS OF (3RS,3'RS)-ALLOXANTHIN AND OTHER ACETYLENES [J].