BIOSYNTHETIC CAPACITIES OF ACTINOMYCETES .2. JUGLOMYCIN-Z, A NEW NAPHTHOQUINONE ANTIBIOTIC FROM STREPTOMYCES-TENDAE

被引：15

作者：

FIEDLER, HP ^{[1
]}

KULIK, A ^{[1
]}

SCHUZ, TC ^{[1
]}

机构：

[1] UNIV GOTTINGEN,INST ORGAN CHEM,D-37077 GOTTINGEN,GERMANY

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 10期

关键词：

D O I：

10.7164/antibiotics.47.1116

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new juglomycin-type antibiotic was identified by a HPLC-diode array screening technique in the culture filtrate of Streptomyces tendae Tu 901/8c. Juglomycin Z (1) differs from all other known juglomycin compounds by an additional methyl group in position 3 of the naphthoquinone ring system. Juglomycin Z is antibiotically active against Gram-positive and Gram-negative bacteria and against yeasts.

引用

页码：1116 / 1122

页数：7

共 12 条

[1]

Fiedler H-P., 1993, CUTANEOUS ANTIFUNGAL, P325

[2] SCREENING FOR NEW MICROBIAL PRODUCTS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY USING A PHOTODIODE ARRAY DETECTOR [J].

FIEDLER, HP .

JOURNAL OF CHROMATOGRAPHY, 1984, 316 (DEC) :487-494

[3]

FIEDLER HP, 1993, NAT PROD LETT, V2, P119

[4]

HEGETRESKATIS D, 1992, APPL MICROBIOL BIOT, V36, P440

[5]

HELMCHEN G, 1974, TETRAHEDRON LETT, V16, P1527

[6]

KRUPA J, 1989, Z NATURFORSCH B, V44, P345

[7]

KURTH R, 1981, THESIS U TUBINGEN

[8]

LANGHARIG J, 1978, THESIS U TUBINGEN

[9]

LESSMANN H, 1989, Z NATURFORSCH B, V44, P353

[10]

SIEVERT HJP, 1993, DIODE ARRAY DETECTIO, P51

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