IN-VITRO IN-VIVO MODELS FOR PEPTIDE ORAL ABSORPTION - COMPARISON OF CACO-2 CELL-PERMEABILITY WITH RAT INTESTINAL-ABSORPTION OF RENIN INHIBITORY PEPTIDES

被引:44
作者
CONRADI, RA [1 ]
WILKINSON, KF [1 ]
RUSH, BD [1 ]
HILGERS, AR [1 ]
RUWART, MJ [1 ]
BURTON, PS [1 ]
机构
[1] UPJOHN CO,UPJOHN LABS,KALAMAZOO,MI 49001
关键词
PEPTIDE; ORAL ABSORPTION; IN-VITRO IN-VIVO CORRELATION; CELL MONOLAYER; CACO-2;
D O I
10.1023/A:1018990602102
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:1790 / 1792
页数:3
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