STUDIES ON THE CONSTITUENTS OF UMBELLIFERAE PLANTS .18. MINOR CONSTITUENTS OF BUPLEURI RADIX - OCCURRENCE OF SAIKOGENINS, POLYHYDROXYSTEROLS, A TRIHYDROXY-C18 FATTY-ACID, A LIGNAN AND A NEW CHROMONE

Bupleuri radix, an important crude drug in the prescriptions of Chinese traditional medicine, was found to contain small amounts of previously unrecorded constituents, three saikogenins (1, 2 and 3), two polyhydroxysterols (4 and 5), one trihydroxy fatty acid (6a), one lignan (7a), and one simple new chromone, designated saikochromone A (8). These results represent a more complex profile of the chemical constituents of Bupleuri Radix, than was previously known. © 1990, The Pharmaceutical Society of Japan. All rights reserved.