CLONING AND SEQUENCE-ANALYSIS OF THE CDNA FOR BOVINE MITOCHONDRIAL TRANSLATIONAL INITIATION-FACTOR-2

被引：20

作者：

MA, JH

FARWELL, MA

BURKHART, WA

SPREMULLI, LL

机构：

[1] UNIV N CAROLINA,DEPT CHEM,CHAPEL HILL,NC

[2] UNIV N CAROLINA,LINEBERGER COMPREHENS CANC CTR,CHAPEL HILL,NC 27599

[3] E CAROLINA UNIV,DEPT BIOL,GREENVILLE,NC 27834

[4] GLAXO RES INST,DEPT BIOANALYT & STRUCT CHEM,RES TRIANGLE PK,NC

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1261卷 / 02期

关键词：

IF-2; MITOCHONDRION; TRANSLATIONAL INITIATION; 3'-RACE PCR; RT-PCR; (BOVINE);

D O I：

10.1016/0167-4781(95)00041-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The complete sequence of the cDNA encoding bovine mitochondrial translational initiation factor 2 (IF-2(mt)) has been obtained by library screening followed by 3'-RACE PCR. The open reading frame for bovine IF-2(mt) encodes a protein of 727 amino acids. The sequence of bovine IF-2(mt) exhibits 85% identity to human IF-2(mt), but only 38% identity to yeast IF-2(mt) and 39% identity to Escherichia coli IF-2 alpha.

引用

页码：321 / 324

页数：4

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