SYNTHESES OF RACEMIC [ALANINE-1-C-11] AND PARTIALLY RESOLVED [ALANINE-3-C-11]

被引：33

作者：

LANGSTROM, B

STRIDSBERG, B

机构：

[1] Department of Organic Chemistry, Institute of Chemistry, University of Uppsala, S-751 21 Uppsala

来源：

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1979年 / 30卷 / 03期

关键词：

D O I：

10.1016/0020-708X(79)90122-4

中图分类号：

TL [原子能技术]; O571 [原子核物理学];

学科分类号：

0827 ; 082701 ;

摘要：

Irradiation of N2(g) with 10 MeV protons gave [11C]-carbon dioxide which was used as such in the synthesis of racemic [1-11C]-alanine. Alternatively it was transformed to [11C]-methyl iodide for the asymmetric synthesis of [3-11C]-alanine, giving the L(+) form in excess, the ratio L(+)/D(-) being 2.9. The syntheses were completed in 20 and 60 min, respectively. © 1979.

引用

页码：151 / 153

页数：3

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