RAPID ACTIONS OF VITAMIN-D COMPOUNDS

被引:85
|
作者
DEBOLAND, AR [1 ]
NEMERE, I [1 ]
机构
[1] UNIV NACL SUR,DEPT BIOL,RA-8000 BAHIA BLANCA,ARGENTINA
关键词
STEROID HORMONES; NON-GENOMIC MECHANISMS; SIGNAL TRANSDUCTION; NONNUCLEAR RECEPTORS; MEMBRANOPHILIC EFFECTS;
D O I
10.1002/jcb.240490107
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The rapid actions of vitamin D compounds are surveyed in a variety of target tissues, including intestine, muscle, bone, hepatocytes, fibroblasts, HL-60 cells, kidney, mammary gland, and parathyroid. Evidence for non-nuclear receptors vs. membranophilic effects is discussed, followed by a consideration of signal transduction mechanisms including steroid hormone activated Ca2+ channels, phospholipid metabolism, protein kinases, and the role of G-proteins.
引用
收藏
页码:32 / 36
页数:5
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