RAPID ACTIONS OF VITAMIN-D COMPOUNDS

被引:85
|
作者
DEBOLAND, AR [1 ]
NEMERE, I [1 ]
机构
[1] UNIV NACL SUR,DEPT BIOL,RA-8000 BAHIA BLANCA,ARGENTINA
关键词
STEROID HORMONES; NON-GENOMIC MECHANISMS; SIGNAL TRANSDUCTION; NONNUCLEAR RECEPTORS; MEMBRANOPHILIC EFFECTS;
D O I
10.1002/jcb.240490107
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The rapid actions of vitamin D compounds are surveyed in a variety of target tissues, including intestine, muscle, bone, hepatocytes, fibroblasts, HL-60 cells, kidney, mammary gland, and parathyroid. Evidence for non-nuclear receptors vs. membranophilic effects is discussed, followed by a consideration of signal transduction mechanisms including steroid hormone activated Ca2+ channels, phospholipid metabolism, protein kinases, and the role of G-proteins.
引用
收藏
页码:32 / 36
页数:5
相关论文
共 50 条
  • [21] Contributions of Sunlight and Diet to Vitamin D Status
    Macdonald, Helen M.
    CALCIFIED TISSUE INTERNATIONAL, 2013, 92 (02) : 163 - 176
  • [22] Contributions of Sunlight and Diet to Vitamin D Status
    Helen M. Macdonald
    Calcified Tissue International, 2013, 92 : 163 - 176
  • [23] Multiple molecular mechanisms of 1α,25(OH)2-vitamin D3 rapid modulation of three ion channel activities in osteoblasts
    Zanello, LP
    Norman, AW
    BONE, 2003, 33 (01) : 71 - 79
  • [24] Actions of 1,25(OH)2-vitamin D3 on the cellular cycle depend on VDR and p38 MAPK in skeletal muscle cells
    Irazoqui, Ana P.
    Boland, Ricardo L.
    Buitrago, Claudia G.
    JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2014, 53 (03) : 331 - 343
  • [25] Nongenomic signaling by vitamin D - A new face of Src
    Gniadecki, R
    BIOCHEMICAL PHARMACOLOGY, 1998, 56 (10) : 1273 - 1277
  • [26] Molecular biological aspects and signaling pathways of vitamin D
    Mentrup, B.
    Ebert, R.
    Walther, J. N.
    Klotz, B.
    Jakob, F.
    OSTEOLOGIE, 2011, 20 (04) : 293 - 298
  • [27] Vitamin D's role in cell proliferation and differentiation
    Samuel, Sam
    Sitrin, Michael D.
    NUTRITION REVIEWS, 2008, 66 (10) : S116 - S124
  • [28] Involvement of Src in the vitamin D signaling in human keratinocytes
    Gniadecki, R
    BIOCHEMICAL PHARMACOLOGY, 1998, 55 (04) : 499 - 503
  • [29] Vitamin D modulates airway smooth muscle function in COPD
    Banerjee, Audreesh
    Panettieri, Reynold, Jr.
    CURRENT OPINION IN PHARMACOLOGY, 2012, 12 (03) : 266 - 274
  • [30] The Association of Vitamin D with Brain Cognitive Functions: A Literature Review
    Alzahrani, Yahya A.
    Alomary, Mohammed A.
    Alzahrani, Abdulmajeed A.
    Eskandarani, Mawaddah M.
    Aljabry, Iman S.
    Alzahrani, Yahya M.
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2020, 32 (35) : 97 - 113