IRREVERSIBLE ENZYME INHIBITORS .145. PROTEOLYTIC ENZYMES .8. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN DERIVED FROM ALPHA-(2-CARBOXY-4-CHLOROPHENOXY)ACETAMIDE BEARING A TERMINAL SULFONYL FLUORIDE

被引：15

|

作者：

BAKER, BR

HURLBUT, JA

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 01期

关键词：

D O I：

10.1021/jm00301a030

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

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页码：118 / &

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共 32 条

[1] IRREVERSIBLE ENZYME INHIBITORS .114. PROTEOLYTIC ENZYMES .4. ADDITIONAL ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN DERIVED FROM PHENOXYACETAMIDES BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
HURLBUT, JA
JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) : 241 - &
[2] IRREVERSIBLE ENZYME INHIBITORS .113. PROTEOLYTIC ENZYMES .3. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN DERIVED FROM PHENOXYACETAMIDES WITH AN N-FLUOROSULFONYLPHENYL SUBSTITUENT
BAKER, BR
HURLBUT, JA
JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) : 233 - &
[3] IRREVERSIBLE ENZYME INHIBITORS .124. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF XANTHINE OXIDASE DERIVED FROM 2-(AND 8-) BENZYLTHIOPURINES BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
KOZMA, JA
JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) : 652 - &
[4] IRREVERSIBLE ENZYME INHIBITORS .148. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF GUANINE DEAMINASE DERIVED FROM 9-PHENYLGUANINE BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
WOOD, WF
JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) : 216 - &
[5] IRREVERSIBLE ENZYME INHIBITORS .115. PROTEOLYTIC ENZYMES .5. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF TRYPSIN DERIVED FROM P-(PHENOXYALKOXY)BENZAMIDINES WITH A TERMINAL SULFONYL FLUORIDE
BAKER, BR
ERICKSON, EH
JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) : 245 - &
[6] IRREVERSIBLE ENZYME INHIBITORS .185. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF GUANINE DEAMINASE DERIVED FROM 9-PHENYLGUANINE BEARING A TERMINAL SULFONYL FLUORIDE .2.
BAKER, BR
SIEBENEICK, HU
JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (09) : 802 - +
[7] IRREVERSIBLE ENZYME INHIBITORS .172. PROTEOLYTIC ENZYMES .16. COVALENT BONDING OF SULFONYL FLUORIDE GROUP TO SERINE OUTSIDE ACTIVE SITE OF ALPHA-CHYMOTRYPSIN BY EXO-TYPE ACTIVE-SITE DIRECTED IRREVERSIBLE INHIBITORS
CARDINAU.R
BAKER, BR
JOURNAL OF MEDICINAL CHEMISTRY, 1970, 13 (03) : 467 - &
[8] IRREVERSIBLE ENZYME INHIBITORS . 144 . PROTEOLYTIC ENZYMES .7. ADDITIONAL ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF TRYPSIN DERIVED FROM M- AND P-(PHENOXYALKOXY)BENZAMIDINES WITH A TERMINAL SULFONYL FLUORIDE
BAKER, BR
ERICKSON, EH
JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 112 - &
[9] IRREVERSIBLE ENZYME INHIBITORS .156. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF XANTHINE OXIDASE DERIVED FROM 9-(ACYLAMIDOPHENYL)GUANINES SUBSTITUTED WITH A TERMINAL SULFONYL FLUORIDE
BAKER, BR
WOOD, WF
JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) : 211 - &
[10] IRREVERSIBLE ENZYME INHIBITORS .150. PROTEOLYTIC ENZYMES .9. (3,4-DICHLOROPHENOXYACETAMIDO)PYRIDINES BRIDGED BY A QUATERNARY SALT TO A TERMINAL SULFONYL FLUORIDE . POTENT IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN
BAKER, BR
HURLBUT, JA
JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) : 221 - &

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