ON THE BROMINATION OF HYPERICIN - THE GYMNOCHROME CHROMOPHORES

被引：29

作者：

FALK, H

SCHMITZBERGER, W

机构：

[1] Institut für Chemie, Johannes Kepler Universität Linz, Linz

来源：

MONATSHEFTE FUR CHEMIE | 1993年 / 124卷 / 01期

关键词：

BROMO-HYPERICINES; GYMNOCHROMES; H-1-NMR; C-13-NMR; UV-VIS; PK(A) VALUES; FLUORESCENCE;

D O I：

10.1007/BF00808512

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Stepwise electrophilic bromination of hypericin in pyridine as the solvent yields regioselectively 2,5-dibromohypericin, 2,5,9-tribromohypericin, and 2,5,9,12-tetrabromohypericin. The compounds were characterized by means of NMR-, UV-Vis-, and fluorescence-spectra, and pK(a) and pK(a)* measurements. These properties were compared with those of hypericin on the one hand and of the recently isolated gymnochromes on the other hand.

引用

页码：77 / 81

页数：5

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