ENTEROAGGREGATIVE ESCHERICHIA-COLI STRAINS SECRETE A HEAT-LABILE TOXIN ANTIGENICALLY RELATED TO ESCHERICHIA-COLI HEMOLYSIN

被引：53
|
作者：
BALDWIN, TJ
KNUTTON, S
SELLERS, L
HERNANDEZ, HAM
AITKEN, A
WILLIAMS, PH
机构：
[1] UNIV BIRMINGHAM,INST CHILD HLTH,BIRMINGHAM B16 8ET,ENGLAND
[2] UNIV LEICESTER,DEPT GENET,LEICESTER LE1 7RH,ENGLAND
[3] NATL INST MED RES,LONDON NW7 1AA,ENGLAND
来源：
INFECTION AND IMMUNITY | 1992年 / 60卷 / 05期
基金：
英国惠康基金;
关键词：
D O I：
10.1128/IAI.60.5.2092-2095.1992
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A protein toxin of approximately 120,000 Da secreted by nonhemolytic enteroaggregative Escherichia coli strains cross-reacted in Western blots (immunoblots) with antibodies raised against the C-terminal region of E. coli hemolysin. Treatment of HEp-2 cells with enteroaggregative E. coli or culture supernatants caused elevation of intracellular calcium and stimulated calcium-dependent protein phosphorylation.
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页码：2092 / 2095
页数：4
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