MOENOMYCIN-A - A STRUCTURAL REVISION AND NEW STRUCTURE-ACTIVITY RELATIONS

被引:44
作者
FEHLHABER, HW
GIRG, M
SEIBERT, G
HOBERT, K
WELZEL, P
VANHEIJENOORT, Y
VANHEIJENOORT, J
机构
[1] UNIV PARIS 11,F-91405 ORSAY,FRANCE
[2] RUHR UNIV BOCHUM,FAK CHEM,W-4630 BOCHUM 1,GERMANY
关键词
D O I
10.1016/S0040-4020(01)81965-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A detailed FAB MS analysis combined with NMR and chemical results requires the structure of moenomycin A to be revised from 1a to 1b. New bio-chemical results seem to support the assumption that in the region F-G-H of lb the structural requirements for antibiotic activity are rather strict. © 1990.
引用
收藏
页码:1557 / 1568
页数:12
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