Data on this paper show the concentrations of COD, BOD5, TSS, K+, Ca2+, Na+, Cl-, NO3-, PO42+, Mn2+, Fe2+, Mg2+, Zn2+, Ni, Pb, Cu and Cd in the influent and effluent of wastewater, and also the nematode eggs, total and fecal coliform in effluents from wastewater treatment plant of Rasht, Guilan Province, in Iran. Measurements of pollutants in influent and effluent was measured according to standard methods (W.E. Federation and Association, A. P. H., 2005) [1]. Statistical analysis of the data was carried out using Special Package for Social Sciences (SPSS 16). Published by Elsevier Inc.