PNEUMOCYSTIS-CARINII PNEUMONIA DURING PRIMARY HIV-1 INFECTION

被引：51

作者：

VENTO, S

DIPERRI, G

GAROFANO, T

CONCIA, E

BASSETTI, D

机构：

[1] UNIV VERONA,DEPT INFECT DIS,I-37100 VERONA,ITALY

[2] A PUGLIESE HOSP,INFECT DIS UNIT,CATANZARO,ITALY

[3] UNIV GENOA,DEPT INFECT DIS 1,I-16126 GENOA,ITALY

来源：

LANCET | 1993年 / 342卷 / 8862期

关键词：

D O I：

10.1016/0140-6736(93)91884-O

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

3 patients with severe CD4 lymphocytopenia (62-91 cells/muL) and inverted CD4/CD8 ratios (0.13-0.15) developed Pneumocystis carinii pneumonia during symptomatic, primary HIV-1 infection. Within four months of symptom onset, their CD4 counts and CD4/CD8 ratios returned to normal. Twenty-nine to forty-eight months after acquiring HIV-1 infection, they show no signs or symptoms of progression to AIDS. Pneumocystis carinii pneumonia can occur, therefore, in primary HIV-1 infection, and profound CD4 lymphocytopenia can revert to normal without antiretroviral therapy.

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页码：24 / 25

页数：2

相关论文

共 10 条

[1] HIGH TITERS OF CYTOPATHIC VIRUS IN PLASMA OF PATIENTS WITH SYMPTOMATIC PRIMARY HIV-1 INFECTION [J].

CLARK, SJ ;

SAAG, MS ;

DECKER, WD ;

CAMPBELLHILL, S ;

ROBERSON, JL ;

VELDKAMP, PJ ;

KAPPES, JC ;

HAHN, BH ;

SHAW, GM .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (14) :954-960

[2] CLINICAL PICTURE OF PRIMARY HIV INFECTION PRESENTING AS A GLANDULAR-FEVER-LIKE ILLNESS [J].

GAINES, H ;

VONSYDOW, M ;

PEHRSON, PO ;

LUNDBERGH, P .

BRITISH MEDICAL JOURNAL, 1988, 297 (6660) :1363-1368

[3] IMMUNOLOGICAL CHANGES IN PRIMARY HIV-1 INFECTION [J].

GAINES, H ;

VONSYDOW, MAE ;

VONSTEDINGK, LV ;

BIBERFELD, G ;

BOTTIGER, B ;

HANSSON, LO ;

LUNDBERGH, P ;

SONNERBORG, AB ;

WASSERMAN, J ;

STRANNEGARD, OO .

AIDS, 1990, 4 (10) :995-999

[4] CLINICAL COURSE OF PRIMARY HIV INFECTION - CONSEQUENCES FOR SUBSEQUENT COURSE OF INFECTION [J].

PEDERSEN, C ;

LINDHARDT, BO ;

JENSEN, BL ;

LAURITZEN, E ;

GERSTOFT, J ;

DICKMEISS, E ;

GAUB, J ;

SCHEIBEL, E ;

KARLSMARK, T .

BRITISH MEDICAL JOURNAL, 1989, 299 (6692) :154-157

[5] CANDIDA ESOPHAGITIS ASSOCIATED WITH ACUTE HUMAN IMMUNODEFICIENCY VIRUS-INFECTION [J].

PEDERSEN, C ;

GERSTOFT, J ;

LINDHARDT, BO ;

SINDRUP, J .

JOURNAL OF INFECTIOUS DISEASES, 1987, 156 (03) :529-530

[6] SUSCEPTIBILITY TO AIDS PROGRESSION APPEARS EARLY IN HIV-INFECTION [J].

SCHECHTER, MT ;

CRAIB, KJP ;

LE, TN ;

MONTANER, JSG ;

DOUGLAS, B ;

SESTAK, P ;

WILLOUGHBY, B ;

OSHAUGHNESSY, MV .

AIDS, 1990, 4 (03) :185-190

[7] CHARACTERIZATION OF THE ACUTE CLINICAL ILLNESS ASSOCIATED WITH HUMAN IMMUNODEFICIENCY VIRUS-INFECTION [J].

TINDALL, B ;

BARKER, S ;

DONOVAN, B ;

BARNES, T ;

ROBERTS, J ;

KRONENBERG, C ;

GOLD, J ;

PENNY, R ;

COOPER, D .

ARCHIVES OF INTERNAL MEDICINE, 1988, 148 (04) :945-949

[8] PRIMARY HIV-INFECTION - HOST RESPONSES AND INTERVENTION STRATEGIES [J].

TINDALL, B ;

COOPER, DA .

AIDS, 1991, 5 (01) :1-14

[9] SEVERE CLINICAL MANIFESTATIONS OF PRIMARY HIV INFECTION [J].

TINDALL, B ;

HING, M ;

EDWARDS, P ;

BARNES, T ;

MACKIE, A ;

COOPER, DA .

AIDS, 1989, 3 (11) :747-749

[10]

1986, MMWR, V35, P334