IMMUNE-RESPONSES IN HIV-EXPOSED SERONEGATIVES - HAVE THEY REPELLED THE VIRUS

被引：161

作者：

ROWLANDJONES, SL

MCMICHAEL, A

机构：

[1] SL Rowland-Jones and AJ McMichael, Molecular Immunology Group, Institute of Molecular Medicine, Oxford, OX3 9DU, Headington

来源：

CURRENT OPINION IN IMMUNOLOGY | 1995年 / 7卷 / 04期

关键词：

D O I：

10.1016/0952-7915(95)80087-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Over the past two years, a number of reports have described specific cellular immune responses to HIV in some individuals who, despite exposure to the virus, remain uninfected. A recent description of virus disappearance in a child born to an infected mother should be seen against the background of several previous studies that have hinted at the possibility of clearance of HIV. These findings suggest that immune-mediated clearance of virus may occur in a few fortunate individuals.

引用

页码：448 / 455

页数：8

共 63 条

[11] TRANSIENT ANTIBODY TO LYMPHADENOPATHY-ASSOCIATED VIRUS HUMAN T-LYMPHOTROPIC VIRUS TYPE-III AND LYMPHOCYTE-T ABNORMALITIES IN THE WIFE OF A MAN WHO DEVELOPED THE ACQUIRED IMMUNODEFICIENCY SYNDROME [J].

BURGER, H ;

WEISER, B ;

ROBINSON, WS ;

LIFSON, J ;

ENGLEMAN, E ;

ROUZIOUX, C ;

BRUNVEZINET, F ;

BARRESINOUSSI, F ;

MONTAGNIER, L ;

CHERMANN, JC .

ANNALS OF INTERNAL MEDICINE, 1985, 103 (04) :545-547

[12]

CHAN WL, 1995, AIDS, V9, P223, DOI 10.1097/00002030-199509030-00002

[13] PROTECTION IN SIMIAN IMMUNODEFICIENCY VIRUS VACCINATED MONKEYS CORRELATES WITH ANTI-HLA CLASS-I ANTIBODY-RESPONSE [J].

CHAN, WL ;

RODGERS, A ;

HANCOCK, RD ;

TAFFS, F ;

KITCHIN, P ;

FARRAR, G ;

LIEW, FY .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 176 (04) :1203-1207

[14] CYTOTOXIC LYMPHOCYTE-T RESPONSES IN THE PERIPHERAL-BLOOD OF CHILDREN BORN TO HUMAN IMMUNODEFICIENCY VIRUS-1-INFECTED MOTHERS [J].

CHEYNIER, R ;

LANGLADEDEMOYEN, P ;

MARESCOT, MR ;

BLANCHE, S ;

BLONDIN, G ;

WAINHOBSON, S ;

GRISCELLI, C ;

VILMER, E ;

PLATA, F .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1992, 22 (09) :2211-2217

[15] HIV-SPECIFIC T-HELPER ACTIVITY IN SERONEGATIVE HEALTH-CARE WORKERS EXPOSED TO CONTAMINATED BLOOD [J].

CLERICI, M ;

LEVIN, JM ;

KESSLER, HA ;

HARRIS, A ;

BERZOFSKY, JA ;

LANDAY, AL ;

SHEARER, GM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 271 (01) :42-46

[16] CELL-MEDIATED IMMUNE-RESPONSE TO HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) TYPE-1 IN SERONEGATIVE HOMOSEXUAL MEN WITH RECENT SEXUAL EXPOSURE TO HIV-1 [J].

CLERICI, M ;

GIORGI, JV ;

CHOU, CC ;

GUDEMAN, VK ;

ZACK, JA ;

GUPTA, P ;

HO, HN ;

NISHANIAN, PG ;

BERZOFSKY, JA ;

SHEARER, GM .

JOURNAL OF INFECTIOUS DISEASES, 1992, 165 (06) :1012-1019

[17] CELLULAR IMMUNE FACTORS ASSOCIATED WITH MOTHER-TO-INFANT TRANSMISSION OF HIV [J].

CLERICI, M ;

SISON, AV ;

BERZOFSKY, JA ;

RAKUSAN, TA ;

BRANDT, CD ;

ELLAURIE, M ;

VILLA, M ;

COLIE, C ;

VENZON, DJ ;

SEVER, JL ;

SHEARER, GM .

AIDS, 1993, 7 (11) :1427-1433

[18] T-CELL PROLIFERATION TO SUBINFECTIOUS SIV CORRELATES WITH LACK OF INFECTION AFTER CHALLENGE OF MACAQUES [J].

CLERICI, M ;

CLARK, EA ;

POLACINO, P ;

AXBERG, I ;

KULLER, L ;

CASEY, NI ;

MORTON, WR ;

SHEARER, GM ;

BENVENISTE, RE .

AIDS, 1994, 8 (10) :1391-1395

[19]

CLERICI M, 1991, J IMMUNOL, V146, P2214

[20] A T(H)1-]T(H)2 SWITCH IS A CRITICAL STEP IN THE ETIOLOGY OF HIV-INFECTION [J].

CLERICI, M ;

SHEARER, GM .

IMMUNOLOGY TODAY, 1993, 14 (03) :107-110

← 1 2 3 4 5 6 7 →