RENAL-FUNCTION OF WORKERS WITH LOW-LEVEL CADMIUM EXPOSURE

被引：34

作者：

VERSCHOOR, M ^{[1
]}

HERBER, R ^{[1
]}

VANHEMMEN, J ^{[1
]}

WIBOWO, A ^{[1
]}

ZIELHUIS, R ^{[1
]}

机构：

[1] TNO,MED BIOL LAB,2280 HV RIJSWIJK,NETHERLANDS

来源：

SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH | 1987年 / 13卷 / 03期

关键词：

BIOLOGICAL MATERIALS - Chemical Analysis - INDUSTRIAL HYGIENE - PROTEINS - Chemical Analysis;

D O I：

10.5271/sjweh.2065

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The influence of occupational exposure to cadmium on renal function was examined in 27 male cadmium workers from plants with second-degree usage of cadmium. The levels of cadmium in the blood and urine and various protein concentrations in the urine and serum were determined. The urinary levels of beta //2-microglobulin, retinol-binding protein, and N-acetyl- beta -D-glucosaminidase were statistically significantly increased in workers with urinary cadmium levels above 50 nmol/l. SDS-PAGE electrophoresis with silver staining is probably a sensitive indicator of the early effects of cadmium on protein excretion. The currently recommended biological exposure limits may have to be lowered.

引用

页码：232 / 238

页数：7

共 28 条

[1] RELIABILITY OF URINARY CREATININE AS A PARAMETER USED TO ADJUST VALUES OF URINARY BIOLOGICAL INDICATORS [J].