Composite type A thymoma and diffuse large B-cell lymphoma

被引：2

作者：

Chen, Hsin-I ^{[1
]}

Chai, Chee-Yin ^{[1
,2
,3
]}

Cho, Shih-Feng ^{[2
,4
]}

Lee, Jui-Ying ^{[2
,5
]}

Chen, Wan-Tzu ^{[1
]}

Wu, Chun-Chieh ^{[1
]}

机构：

[1] Kaohsiung Med Univ Hosp, Dept Pathol, 100 Tzyou 1st Rd, Kaohsiung, Taiwan

[2] Kaohsiung Med Univ, Kaohsiung, Taiwan

[3] Kaohsiung Med Univ, Coll Med, Fac Med, Dept Pathol, Kaohsiung, Taiwan

[4] Kaohsiung Med Univ Hosp, Dept Internal Med, Div Hematol & Oncol, Kaohsiung, Taiwan

[5] Kaohsiung Med Univ Hosp, Dept Surg, Div Chest Surg, Kaohsiung, Taiwan

来源：

TZU CHI MEDICAL JOURNAL | 2015年 / 27卷 / 04期

关键词：

Clonality assay; Composite tumor; Immunohistochemical stain; Lymphoma; Thymoma;

D O I：

10.1016/j.tcmj.2014.05.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The concurrent occurrence of thymoma and diffuse large B-cell lymphoma in the thymus has not been previously reported. We describe a 74-year-old man who presented with general weakness, neck lymphadenopathy, night sweats, and body weight loss. A right anterior mediastinal mass was found on computed tomography of the chest. The immunohistochemical stains AE1/AE3, CD20, CD3, and MUM-1 confirmed the different components of the mediastinal tumor. A heavy-chain gene clonality assay and light-chain gene clonality assay confirmed the B-cell clonality of the mediastinal tumor and neck lymph node. The patient had received a complete course of chemotherapy, and the result of positron emission tomographyecomputed tomography showed complete remission. The pathologic report of this mass revealed composite type A thymoma and diffuse large B-cell lymphoma. If concurrent or composite thymoma and lymphoma are suspected, a thorough examination of the thymoma with a combination of ancillary studies is recommended to rule out the possibility of concurrent lymphoma. Copyright (C) 2014, Buddhist Compassion Relief Tzu Chi Foundation. Published by Elsevier Taiwan LLC. All rights reserved.

引用

页码：177 / 180

页数：4

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